Wegovy injection (semaglutide)
The weekly semaglutide pen. Dose steps from 0.25 mg, heart evidence, storage and missed doses.
- Weekly injection
- semaglutide
- 38 guides
Start here
Wegovy injection in the UK: uses, doses and treatment
Wegovy injection explained for UK readers: licensed uses, the weekly dose plan, side effects, practical care and how it differs from Wegovy tablets.
3 min readWegovy injectionHow Wegovy injection works: appetite, GLP-1 and digestion
How Wegovy changes appetite, fullness and blood glucose, why effects differ between people, and why nausea is a side effect rather than a sign of success.
3 min readWegovy injectionWho can use Wegovy in the UK? Licence and eligibility
The UK Wegovy licence for weight management, heart risk and MASH, the adolescent criteria, and how licence eligibility differs from NHS funding.
3 min readWegovy injectionWegovy weight loss results: reading the STEP trials
Wegovy trial results explained: STEP 1, STEP 5 and STEP UP, average weight loss, how the analyses differ and why cross-trial comparisons mislead.
3 min readWegovy injectionWegovy and heart protection: what the SELECT trial showed
The SELECT trial explained: relative and absolute heart benefit, the UK Wegovy heart indication and how NICE TA1152 differs from obesity prescribing.
3 min readWegovy injectionWegovy for MASH liver disease: the UK licence
Wegovy for non-cirrhotic MASH with F2 to F3 fibrosis in the UK: the ESSENCE trial results, the 2.4 mg dose and what to ask your liver team.
3 min readDoses and your schedule
Wegovy 0.25 mg: your first four weeks
Starting Wegovy at 0.25 mg: preparing for the first injection, setting a weekly routine, eating comfortably and when to contact your prescriber.
3 min readWegovy injectionWegovy 0.5 mg: the second dose stage
What to expect on Wegovy 0.5 mg in weeks 5 to 8: appetite changes, checking your new pen, and reviewing side effects before the next increase.
3 min readWegovy injectionWegovy 1 mg: the middle of the dose build-up
The Wegovy 1 mg stage in weeks 9 to 12: judging progress, checking nutrition and other medicines, and preparing safely for the 1.7 mg dose.
3 min readWegovy injectionWegovy 1.7 mg: getting ready for maintenance
Wegovy 1.7 mg in weeks 13 to 16: reviewing symptoms, avoiding pen mix-ups and planning for long-term maintenance treatment in the UK.
3 min readWegovy injectionWegovy 2.4 mg: the standard maintenance dose
Wegovy 2.4 mg maintenance explained: the trial evidence behind it, ongoing care, and why any move to 7.2 mg is an individual prescribing decision.
3 min readWegovy injectionWegovy 7.2 mg in the UK: eligibility, pens and evidence
Wegovy 7.2 mg in the UK: who qualifies, the single-dose pen, the three-injection option, STEP UP trial results and safety checks before you start.
3 min readWegovy injectionWegovy injection dose schedule in the UK
The UK Wegovy injection schedule from 0.25 mg to 2.4 mg, when a dose rise needs review, and where the restricted 7.2 mg dose fits.
3 min readWegovy injectionMissed Wegovy injection: the five-day rule and longer breaks
What to do after a missed Wegovy injection: the five-day rule, how to change your injection day and why a longer break needs individual restart advice.
3 min readWegovy injectionSwitching to or from Wegovy injections
Switching to or from Wegovy injections: the assessment, avoiding overlap, moving between tablets and pens, and why mg strengths do not convert.
3 min readWegovy injectionMaintaining weight loss on Wegovy
Keeping weight off on Wegovy: realistic goals, eating enough, regular reviews and the limits providers and NHS funding put on long-term treatment.
3 min readWegovy injectionWegovy weight loss plateau: what a stable scale means
Why weight loss stalls on Wegovy: normal ups and downs, the maintenance effect and what to check with your prescriber before you change treatment.
3 min readWegovy injectionStopping Wegovy: appetite, weight regain and planning
What happens when you stop Wegovy: weight regain evidence, appetite changes, the limits of tapering, follow-up and restarting safely later.
3 min readSide effects and safety
Wegovy nausea: practical help and when to seek advice
Practical ways to manage nausea on Wegovy: meal size, fluids, medicine review and the symptoms that need urgent medical assessment.
3 min readWegovy injectionVomiting on Wegovy: when to get urgent help
Vomiting on Wegovy: how to stay hydrated, which warning signs need urgent help, why you never repeat an injection and how to plan your next dose.
3 min readWegovy injectionDiarrhoea on Wegovy: fluids, self-care and warning signs
How to manage diarrhoea on Wegovy: fluids and rehydration, pharmacy medicines, when to call NHS 111 and the effect on the contraceptive pill.
3 min readWegovy injectionWegovy constipation: recognising and managing bowel changes
How to spot and manage constipation on Wegovy, when to ask a pharmacist about laxatives and which bowel symptoms need prompt medical assessment.
3 min readWegovy injectionWegovy heartburn, reflux and burping
Heartburn, reflux and burping on Wegovy: practical relief, what a pharmacist can offer and the chest or swallowing symptoms you must get checked.
3 min readWegovy injectionWegovy and pancreatitis: symptoms, risk and urgent action
Pancreatitis warning signs on Wegovy, what the MHRA safety update in January 2026 said and why severe tummy pain needs urgent assessment.
3 min readWegovy injectionWegovy, gallstones and gallbladder pain
Wegovy and gallstones: symptoms, the part weight loss plays, the tests you may need and when tummy pain, fever or jaundice needs urgent care.
3 min readWegovy injectionWegovy, dehydration and kidney function
How vomiting or diarrhoea on Wegovy can dehydrate you and affect your kidneys, with practical steps, advice on other medicines and urgent warning signs.
3 min readWegovy injectionWegovy and low blood sugar: who is at risk?
Low blood sugar on Wegovy: why insulin and sulfonylureas raise the risk, how to treat a hypo and other reasons you may feel dizzy or shaky.
3 min readWegovy injectionWegovy and eyesight: NAION, diabetes and urgent symptoms
The rare semaglutide link with NAION, how it differs from diabetic retinopathy and when sudden changes in your eyesight need urgent care.
3 min readWegovy injectionWegovy interactions: medicines to raise with your prescriber
Wegovy interactions: insulin and sulfonylureas, warfarin and INR checks, tablet absorption and why you should never double up on GLP-1 medicines.
3 min readUsing it day to day
How to use a Wegovy FlexTouch pen safely
How to use the UK Wegovy FlexTouch pen: device checks, the flow check, setting your dose, injection technique and the common mistakes to avoid.
3 min readWegovy injectionWegovy storage: fridge temperatures, in-use limits and deliveries
How to store Wegovy FlexTouch pens in the UK: fridge temperature, the six-week in-use limit, frozen pens and what to do about a warm delivery.
3 min readWegovy injectionWegovy needles and sharps disposal in the UK
Which needles fit your Wegovy pen, why you use each one once, local sharps collection, leftover medicine and what to do after a needle injury.
3 min readWegovy injectionTravelling with Wegovy injections: a practical checklist
Travelling with Wegovy injections: entry rules, documents, needles, keeping pens cool, time zones and what to do if treatment is delayed abroad.
3 min readPregnancy, contraception and surgery
Wegovy and contraception: the pill, sickness and switching
Wegovy and contraception: how semaglutide rules differ from tirzepatide, what to do after vomiting or diarrhoea, non-oral methods and switching safely.
3 min readWegovy injectionWegovy, pregnancy planning and breastfeeding
UK Wegovy advice on pregnancy: the two-month semaglutide washout, what to do after accidental exposure, breastfeeding and restarting later.
3 min readWegovy injectionWegovy before surgery, endoscopy or sedation
Wegovy before surgery or sedation: the aspiration risk, what to tell your anaesthetic team, following their plan and when to restart your doses.
3 min readGetting it in the UK
Wegovy on the NHS: weight management and heart-risk access
How NHS Wegovy access works: specialist obesity care under NICE TA875, the cardiovascular recommendation in TA1152, and differences across the UK.
3 min readWegovy injectionPrivate Wegovy assessment: what good UK care includes
What good private Wegovy care looks like in the UK: a checked assessment, a registered pharmacy, clinical follow-up, clear costs and safe continuity.
3 min read